Neuronal Cell Biology
Autophagic and endo-lysosomal dysfunction in neurodegenerative disease.
Cancer Cell Biology
Role and regulation of endo-lysosomal system in cancerogenesis.
Correlative Light and Electron Microscopy
Development and Utilization of Correlative Microscopy Techniques for Intracellular Studies
• HOPS and CORVET: Multisubunit tethers of the endo-lysosomal system in health and disease
• Autophagic and endo-lysosomal dysfunction in neurodegenerative diseases
• Lysosomal subpopulations in cancerogenesis
• CHEVI complex in regulation of endo-lysosomal trafficking
• Spatial and temporal regulation of endo-lysosomal processes in lipid metabolism
• Development and Utilization of Correlative Microscopy Techniques for Intracellular Studies